Microbial hosts for metabolic engineering of lignin bioconversion to renewable chemicals

This review discusses the use of engineered microbes for bioconversion lignin from plant biomass to produce renewable chemicals. Existing bacterial hosts are discussed, such as Pseudomonas putida KT2440 and Rhodococcus jostii RHA1, case studies where they have been generate aromatic non-aromatic products described, different types substrates used these studies. Other bacteria identified degraders prospects using other metabolic engineering degradation discussed. Recent advances in genetic modification fungi also which could lead lignin-degrading bioproduct formation lignin. Prospects challenges this field moves laboratory industrial application, including: choice chassis organism, feedstock, complexity polymeric breakdown, considerations scale-up bioproduct. • Case described. A survey is included.